Transfusion related reaction is an adverse event occurring in patients undergoing blood transfusion. It can cause any patients because of the nature of that substance and patient related factors. Health care team members should be aware about these reactions and thereby can reduce these situations and can be managed by using pre medications and other drugs. This study was carried out to identify the transfusion related reactions in our hospital and to analyze the severity, causality relationship, incidence and nature of these reactions. This prospective observational study was carried out among 19 participants using designed data entry form, patient interview, case sheets and laboratory investigations from January 2021 to June 2021 in Navodaya Medical College, Hospital and Research Centre, Raichur. A total of 71 patients were undergoing blood transfusion. TRRs were observed in 19 patients. So the incidence of TRRs in our study was 26.7 %. These TRRs were associated with packed cell RBC. The most commonly caused reactions were edema at the site of injection (47.3%) followed by pruritus at the site of injection (26.3%). Most of these reactions were managed by administering Inj. Dexamethasone, followed by changing the site and administration of Inj. Avil. The study concluded that the causes of these reactions were the patient related factors and the study suggested a need for proper awareness about these reactions to health care professionals. So, they will come to know about the pre medications of these reactions.
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